Of course, using a radioactive additive in a soft drink brought the expected dangers, even with the beverageer's expertise. The isotope was processed into an additive safe for human consumption by another beverageer, Ruth Leavitt. The designation of the strontium sample, Q4N7-UM, resulted in the isotope being named Quantum by its creator, Rex Meacham. In fact, the isotope was so high energy that the beverage it would be added to effectively became sterilized, killing any bacteria with which it came in contact. The origins of this soda were unlike anything the Nuka-Cola Corporation had devised before: 由核子世界饮料开发团队与军方 Army Research Laboratory's Weapon and Material division合作的biological and军用武器项目钴计划过程中制造出的副产品。After months and months of work on several isotopes of strontium, the team discovered the isotope 锶-90 that could weaponize anything in the military's arsenal, but could also act as 添加物让饮料散发吸引人的光芒, similar to Nuka-Cola Quartz and Victory. 游戏文章: Fallout 3, Fallout: New Vegas, Fallout 4, Fallout 76, Fallout Shelter, Fallout: New California Though flat, chilled Nuka-Cola is the recommended way of drinking it. Common before the War, ice cold Nuka-Colas are a luxury item after the Great War, due to the scarcity of working refrigeration units.

Those unable to procure genuine Nuka-Cola bottles can homebrew the drink, with denizens of the southwest able to approximate the taste and properties with Nevada agave and barrel cactus. Even when warm, flat and irradiated, it's the soft drink of choice for many wastelanders. Its popularity endured long after the Great War destroyed the Nuka-Cola Corporation, partly thanks to the sheer number of bottles and cans produced, and partly due to its pleasant flavor.

Although the classic Nuka-Cola remained the most popular, alternative, fruit-flavored beverages were typically an instant success.

Numerous other variants of the classic Nuka-Cola were introduced, offering different flavors and taste profiles.

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